OBJECTIVES OF THE CLUSTER
In order to optimize synergies and avoid overlaps between the projects selected for funding from the call SC1-BHC-27-2018 ‘New testing and screening methods to identify endocrine disrupting chemicals’, the projects will form a cluster.
It is named EURION for “European Cluster to Improve Identification of Endocrine Disruptors”. This cluster was launched on January 1st 2019.
Interactions will be created with other winning ED testing projects with the aim of sharing information and capacities. Partners will contribute to the establishment of a cluster of projects on endocrine disruptors testing in the EU, in order and share expertise and to optimize maximize the impact of ED projects. OBERON partners can provide expertise in different fields such as toxicology, epidemiology, computer sciences and modeling. If needed, partners will assess how to provide access to tools, interpretation capacities and facilities to other selected projects.
CLUSTER COMPOSITION
GOLIATH and OBERON will lead the cluster organization during the first 18 months of the project.
The 8 projects involved in the cluster are:
Logo
Name
Coordinator
Country
Partners
ATHENA
Assays for the identification of Thyroid Hormone axis-disrupting chemicals: Elaborating Novel Assessment strategies
BRUNEL UNIVERSITY LONDON
United-Kingdom
9
EDCMET
Metabolic effects of Endocrine Disrupting Chemicals: novel testing METhods and adverse outcome pathways
University of Eastern Finland
Finland
10
ENDpoiNTs
Novel Testing Strategies for Endocrine Disruptors in the Context of Developmental NeuroToxicity
KAROLINSKA INSTITUTET
Sweden
15
ERGO
Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation
SYDDANSK UNIVERSITET
Danemark
15
FREIA
Female Reproductive toxicity of EDCs: a human evidence-based screening and Identification Approach
UNIVERSITEIT UTRECHT
Netherlands
10
GOLIATH
Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds
UNIVERSITEIT UTRECHT
Netherlands
14
OBERON
An integrative strategy of testing systems for identification of Endocrine Disrupters related to metabolic disorders
INSERM
France
10
SCREENED
Development of three-dimensional (3D) cell-based in vitro tests to better characterize the effects of endocrine disruptors on thyroid functions. This method will overcome the limitations of existing tests, being more sensitive, also at low doses of exposure to chemicals, and enabling the prediction of their toxicity on human health in a sex-specific manner
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